Edinburgh, 1847. A number of young women have been found dead. Medical student Will Raven is about to start his apprenticeship with the renowned Dr Simpson, whose house is full of visiting luminaries and daring experiments. It is here that Raven meets housemaid Sarah Fisher, who recognises trouble when she sees it and takes an immediate dislike to him. With each having their own motive to look deeper into the city's spate of suspicious deaths, Raven and Sarah find themselves propelled headlong into the darkest shadows of Edinburgh's underworld, where they will have to overcome their differences if they are to make it out alive.